ISB News

Awards: Claudia Ludwig Receives AWIS Award

Photo above: ISB’s Claudia Ludwig, MEd (center); Emily Fox, MEng, EE, PhD, for outstanding scientific advancement in STEM (left); Alyssa Taylor, PhD, for excellence in science education (right). Credit: courtesy of AWIS and photographer Martina Machackova Congratulations to Claudia Ludwig, Director of Systems Education Experiences (SEE), on receiving an award from the Seattle chapter of the Association for Women in Science for Excellence in Science Outreach. The ceremony to honor…

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Consilience: Exploring E-Textiles

As part of the Institute for Systems Biology’s annual Consilience event (which took place on May 19, 2017), Afroditi Psarra presented her talk E-textiles: hand-crafting technological artifacts. The Seattle Channel produced the video of the talk. Afroditi Psarra, PhD,  is an assistant professor at DXARTS at the University of Washington. She is a multidisciplinary artist working with e-textiles.  

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Spotlight: Ayodale Braimah, Undergraduate Intern

Congratulations to Ayodale Braimah, an undergraduate intern in the Baliga Lab, who has just been accepted into the medical school at the University of Kansas. Ayodale has been studying microbiology at the University of Washington and sought a position in the Baliga Lab in order to immerse himself in an authentic research experience in microbiology and molecular biology. He specifically wanted to better understand how organisms adapt to new environments….

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‘Scientific American’ Quotes ISB Scientist

Scientific American published an article on the human olfactory system and quoted ISB principal scientist Gustavo Glusman: “Different species specialize in smelling different things, and it’s therefore very hard to compare [them] meaningfully,” Glusman explains. He also points out the brain’s plasticity. “It is well known that when one function is lost, other functions become more nuanced,” such as increased hearing ability after vision loss. Read More

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‘GEN’ Highlights ISB Symposium

In a feature article in “Genetic Engineering & Biotechnology News,” writer Kathy Liszewski takes readers through the minds of systems biologists whom she compares to experts in biological cryptanalysis who are hunting for the “subcellular double agents and moles” behaving nefariously and causing disease. The writer shares some key points from speakers who presented at ISB’s annual Symposium, including ISB assistant professor Dr. Naeha Subramanian and Dr. Trevor Mundel, of…

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ISB Consilience: Museum of Awe

The Museum of Awe is all around us; you just have to find a door. Attendees of the 2017 Consilience event, including ISB’s Dr. Ilya Shmulevich (center), examine a mini “pop-up” experience created by NASA JPL visual strategists Dan Goods and David Delgado. The tank allows people to see particles that have come down to earth from outer space. The experience is designed as a simple reminder of the gift…

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Spotlight: Alison Paquette, Research Scientist

Congratulations to Alison Paquette who recently was promoted to Research Scientist in the Price Lab. Alison received her PhD in Experimental and Molecular Medicine at the Geisel School of Medicine at Dartmouth. She is interested in identifying molecular biomarkers that may predict preterm birth and adverse neonatal outcomes such as preeclampsia. “Pregnancy complications are not very well understood, and we are amongst the only labs really taking a systems biology…

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Martin_Shelton_PhD

ISB Q&A: Martin Shelton, Post-Doctoral Fellow

Dr. Martin Shelton is a post-doctoral fellow in the Hood Lab. Q: What are you currently working on? Our project, which I work on jointly with Rhishikesh Bargaje and Kalliopi Trachana, along with many other great collaborators both within and outside of the ISB, involves measuring the changes that occur within individual cells as populations of those cells transition from one state to another. We use, as a model system,…

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Dr. Lee Hood Receives NAS MEDAL

“Science must be enshrined in our hearts and our minds, for science is the key to inventing a future that has power, beauty, simplicity, and the ability to let all of us reach our potential,” said Dr. Leroy Hood upon receiving the National Academy of Sciences Award for Chemistry in Service to Society, which was awarded on Sunday, April 30. Watch the full acceptance speech here. Read the full citation…

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Spotlight: Christine Pham

Christine Pham, 2016 ISB High School Intern, was accepted by WSU’s Honors College and was named a Distinguished Regents Scholar, which awarded her a four-year tuition scholarship. “ISB saw the potential in me when I had not realized it myself. Working with multiple mentors and lab partners fostered my growth as an individual. As I head to college with the hopes of pursuing an interdisciplinary subject, I will build upon…

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New Publication in Cell Systems

April 25, 2017 A Cell-Surface Membrane Protein Signature for Glioblastoma 3 bullets: Using integrated protein and gene expression data, ISB researchers developed a 33-gene signature for glioblastoma, an aggressive form of brain cancer. Glioblastoma gene signatures are associated with TGF-b signaling and cancer invasion. Researchers think that some of the glioblastoma gene signatures have the potential to be used as blood biomarkers for this aggressive cancer. Read the full summary…

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Institute for Systems Biology Recruits Technology Pioneer James Heath as President

FOR IMMEDIATE RELEASE >> Renowned scientist, visionary leader from Caltech will join Seattle research community SEATTLE, APRIL 3, 2017 – The Institute for Systems Biology has named James Heath, PhD, as its new president, effective January 2018. Heath is widely recognized as one of the world’s most accomplished scientists, working on fundamental problems at the interface of the chemical, physical, biological, and biomedical sciences, with focus areas of molecular biotechnologies…

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Spotlight: Claudia Ludwig

Congratulations to Claudia Ludwig, Director, Systems Education Experiences (SEE), on being named the winner of the 2017 AWIS Award for Excellence in Science Outreach from the Seattle Chapter of Association for Women in Science (AWIS). Claudia, a former high school biology and chemistry teacher, is the Director of Systems Education Experiences at ISB, a program that she has been instrumental in building since she joined ISB in 2004. Because of…

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ISB Q&A: David Gibbs, Research Scientist

You have to have fun. ISB founder Dr. Lee Hood always reminds staff that it’s important to do great work, and it’s also important to have fun. In that spirit, we feature CatterPlots, a “silly idea” that brought a smile to many scientists. Q: What is CatterPlots and how is it used? David Gibbs: The R programming environment is organized around a large collection of software packages. Many packages are…

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2017 Consilience Event

ISB hosts its annual Consilience event on May 19 at 1pm. The theme is “Integrating Diverse Approaches to Communicating the Complexities of Science.” This year’s speakers include Dan Goods and David Delgado from NASA’s Jet Propulsion Laboratory, and Afroditi Psarra from University of Washington. ISB co-founder Dr. Lee Hood will give opening remarks. Featured artist Ginny Ruffner will present her interactive augmented reality installation “Poetic Hybrids.” The goal of the…

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ISB Scientists Have Discovered When and Why a Microbial Community Might Collapse

Researchers in the Baliga Lab at Institute for Systems Biology have developed a framework for assessing the “health” of a microbial community through a stress test that enables them to ask when and why microbial communities collapse under different environmental conditions. The study, published on March 20, 2017, in the journal Molecular Systems Biology, determined that while microbes are equipped to respond to environmental changes, when pushed to the extreme…

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ISB at Town Hall Seattle: The Future of Health

EVENT: ISB Panel on “The Future of Health” DATE: April 3, 2017 TIME: 7:30 p.m. COST: $5 TICKETS: townhallseattle.org/event/isb-panel-2/ Seattle’s Institute for Systems Biology (ISB) is revolutionizing science with a powerful approach to predict and prevent disease, and enable a sustainable environment. Explore the cross-disciplinary and collaborative approach of systems biology and how it is applied in the exploration of new frontiers in biology and medicine. This moderated forum will…

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William Poole, 2013 undergrad intern

Former Undergrad Intern Publishes Algorithm in PLOS Computational Biology

Posted March 1, 2017 In a study published in PLoS Computational Biology, researchers at Institute for Systems Biology (ISB) have developed a multiscale mutation clustering algorithm (M2C) that identifies variable length regions with high mutation density in cancer genes. The M2C algorithm was developed by William Poole (first author on the paper), who started as a summer intern in 2013 as part of ISB’s Center for Systems Biology internship program….

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