ISB News

Bench to Blackboard: Q&A with Dr. Colleen Sheridan

Once an immunologist focusing on research at ISB, Colleen Sheridan followed her passion and became a tenure-track college biology professor focusing on teaching. Sheridan was awarded the Valerie Logan Leadership in Science Education Award, and describes her professional transformation in this Q&A.

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Igniting Curiosity, Catalyzing Change

At the 6th Annual Valerie Logan Luncheon held Thursday, the day’s theme – “Igniting Curiosity, Catalyzing Change” – was evident throughout. Every year, ISB celebrates Valerie Logan, the founder of our education programs, and all her work toward providing K-16 professional development for educators, high school STEM curriculum development, undergraduate research internships, and, crucially, student access to diverse mentors. This year’s event raised a record $140,000 to fund ISB’s education programs.

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‘Pushing Cancer Research Forward:’ Powerful ISB Cancer Genomics Cloud Tool in Spotlight

Institute for Systems Biology, Google and CSRA have jointly created a cloud-based platform that allows researchers to quickly, reliably and securely access massive amounts of data in ways that, until now, haven’t been possible.

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Translational Research Fellows Program

ISB, Providence St. Joseph Health Launch Translational Research Fellows Program

ISB and Providence St. Joseph Health are leveraging their respective research and clinical expertise to attract exceptional individuals into the Translational Research Fellows Program, a three-year training program that offers early-stage scientists a chance to jumpstart their careers and provides mentorship from experts in systems biology and clinical research.

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Genome fingerprinting

Genome Comparison Easier with ‘Fingerprint’ Method

ISB researchers have developed a method of capturing a personal genome as a “fingerprint,” which will have a major impact on how quickly and efficiently genome sequences are compared.

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Postdoc Appreciation 2017

Postdoc Appreciation 2017

In honor of National Postdoc Appreciation Week in late September, ISB’s staff recently gathered to honor and celebrate all of our devoted and hardworking postdocs. The event included speeches from a number of faculty members. “Postdocs are the heart of ISB,” Dr. Nathan Price, professor and associate director, told the gathering.

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2017 ISB Intern Akanksha Bawa

2017 Undergrad Intern Showcase

Summer 2017 brought a fresh cohort of undergraduate students interested in exploring ISB’s research in the Summer Undergraduate Research Experience Program.

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Annual Report 2016

ISB Annual Report: Catalyzing A Revolution

ISB’s compass has always been oriented toward the future. Even when we reflect on the past year for each annual report, it’s always through the lens of what’s on the horizon. We are remarkably consistent in that regard, which is in no small part due to our president Dr. Lee Hood, whose vision is perpetually a decade – at least – ahead of everyone else.

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ISB Artwork Featured On Cover of Nature Biotechnology

Institute for Systems Biology and Arivale “Pioneer 100 Study” is featured on the cover of August’s Nature Biotechnology. The artwork was created by ISB’s Associate Director of Communications Allison Kudla in collaboration with contributing author John C. Earls, software engineer in Hood/Price Lab.

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Warhol style Plasmodium

The Other Malaria: Finding New Targets for a Vaccine Against Plasmodium vivax

A new report in PLOS Neglected Tropical Diseases describes the results of an international collaboration led by researchers at ISB and Seattle’s Center for Infectious Disease Research (CIDResearch). We used mass spectrometry-based proteomics to identify nearly 2,000 proteins present in Plasmodium vivax parasites, one of the Plasmodium species that cause the disease malaria in humans. The work was done on parasites dissected from mosquito salivary glands, parasites that were in…

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Adaptive Prediction of Yeast

New Study on How Microbes Learn to Predict the Future

In a study published in Genome Biology and Evolution, researchers at Institute for Systems Biology (ISB) designed an experiment to evolve novel adaptive prediction capability in yeast by repetitively exposing it to caffeine, followed by a toxin. Remarkably, the yeast cells learned the structure of this novel environmental pattern within as few as 50 generations to use caffeine as a cue for anticipating and mitigating lethal effects of the toxin.

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Pioneer 100 Study

Institute for Systems Biology and Arivale “Pioneer 100 Study” Establishes Foundation for New Industry of Scientific Wellness

Institute for Systems Biology and Arivale “Pioneer 100 Study” Establishes Foundation for New Industry of Scientific Wellness. Personal, dense, dynamic data clouds enable novel insights into mechanisms of wellness and disease, new approaches to biomarker discovery, and the empowerment of individuals to enhance their own health.

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Consilience: The Museum of Awe

As part of the Institute for Systems Biology’s annual Consilience event (which took place on May 19, 2017), Dan Goods and David Delgado presented their talk The Museum of Awe. The Seattle Channel produced the video of the talk. Dan Goods and David Delgado are Visual Strategists at NASA’s Jet Propulsion Laboratory in Pasadena, California.  

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Dr. Jeff Ranish Promoted to Professor

We are pleased to announce the promotion of Jeff Ranish to Professor. Jeff has been a pioneer in the fields of mass spectrometry and gene regulation. His impressive history of innovation in mass spectrometry technology has produced novel protein-crosslinking approaches to identify large scale protein-protein interactions in complex mixtures. He has applied the innovations to important biological problems, resulting in notable findings such as the characterization of multiple topological and…

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Summer Course Success

Among ISB’s core values is the belief that we have a responsibility to share what we know. To that end, ISB hosts an annual weeklong Systems Biology of Disease Summer Course to introduce the core concepts of systems biology and their application to systems biomedicine. The course demonstrates the importance of cross-disciplinary interactions for the success of systems biology programs. Participants include graduate students, postdoctoral fellows, biomedical researchers, educators and…

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Inspiring Teachers to Inspire Students

Featured image: ISB’s Dr. Martin Shelton, left, speaks to administrators from the Central Kitsap School District. ISB’s Logan Center for Education recently kicked off a five-year Principles of Science for Principals (P4P) project with the leadership from the Central Kitsap School District. While many programs and accompanying research have been employed to support science teachers in advancing their practice, there have been few programs designed to support principals and their…

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ISB Engineer Hopes to Save the Sword Ferns in Seattle’s Magnificent Forest

Seattle’s Magnificent Forest at Seward Park is located within one of the nation’s most diverse neighborhoods. The 98118 zip code in southeast Seattle is home to people of all socioeconomic classes including groups of immigrants who speak more than 60 languages. Seward Park serves as an urban oasis for the community to enjoy nature, easy hikes, and access to the expansive Lake Washington. The park’s Magnificent Forest, so called because…

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TCGA, ISB Researchers Identify Potential Drug Targets for Leading Form of Deadly Liver Cancer

June 19, 2017 Researchers in ISB’s Shmulevich Lab and their colleagues in The Cancer Genome Atlas Research Network performed the first large-scale, multi-platform analysis of hepatocellular carcinoma, the predominant form of liver cancer. Study was published on June 15, 2017, in the journal Cell. 3 Bullets: Liver cancer is the second most common cause of death from cancer worldwide. ISB researchers and colleagues from The Cancer Genome Atlas Research Network…

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