Dr. Hood’s outstanding contributions have had a resounding effect on the advancement of science since the 1960s. Throughout his career, he has adhered to the advice of his mentor, Dr. William J. Dreyer: “If you want to practice biology, do it on the leading edge, and if you want to be on the leading edge, invent new tools for deciphering biological information.”
Hood was involved in the development of five instruments critical for contemporary biology—namely, automated DNA sequencers, DNA synthesizers, protein sequencers, peptide synthesizers, and an ink jet printer for constructing DNA arrays. These instruments opened the door to high-throughput biological data and the era of big data in biology and medicine. He helped pioneer the human genome program—making it possible with the automated DNA sequencer. Under Hood’s direction, the Human Genome Center sequenced portions of human chromosomes 14 and 15.
In 1992, Hood created the first cross-disciplinary biology department, Molecular Biotechnology, at the University of Washington. In 2000, he left the UW to co-found Institute for Systems Biology, the first of its kind. He has pioneered systems medicine the years since ISB’s founding. Hood has made many seminal discoveries in the fields of immunology, neurobiology and biotechnology and, most recently, has been a leader in the development of systems biology, its applications to cancer, neurodegenerative disease, and the linkage of systems biology to personalized medicine.
Hood is now pioneering new approaches to P4 medicine—predictive, preventive, personalized and participatory, and most recently, has embarked on creating a P4 pilot project on 100,000 well individuals, that is transforming healthcare.
In addition to his ground-breaking research, Hood has published 750 papers, received 36 patents, 17 honorary degrees and more than 100 awards and honors. He is one of only 15 individuals elected to all three National Academies—the National Academy of Science, the National Academy of Engineering, and the Institute of Medicine. Hood has founded or co-founded 15 different biotechnology companies including Amgen, Applied Biosystems, Rosetta, Darwin, Integrated Diagnostics, Indi Molecular and Arivale.
2015 The Johns Hopkins University Alumni Association Global Achievement Award
2014 Institute of Electrical and Electronics Engineers Medal for Innovations in Healthcare Technology
2014 Geoffrey Beene Builders of Science award presented by Research!America
2013 Alvin J. Thompson Award for Leadership in K-12 education and science (awarded by NW Assoc. for Biomed Research)
2013 Future in Review, CEO of the year
2012 Elected as a Fellow to the American Association for Cancer Research
2011 National Medal of Science
2011 Fritz and Dolores Russ Prize, National Academy of Engineering
2007 Elected Member, National Academy of Engineering
2007 Elected Member, Inventors Hall of Fame for the automated DNA sequencer
2006 Heinz Award for pioneering work in Systems Biology
2005 AACR-Irving Weinstein Foundation Distinguished Lecturer Award
2003 Elected Member, Institute of Medicine of the National Academy of Science
2003 Lemelson-MIT Prize for Innovation and Invention
2002 Kyoto Prize in Advanced Technology
2000 Elected Member, American Philosophical Society
1993 Scientist of the Year, Research and Development Magazine
1987 Albert Lasker Basic Medical Research Award
1982 Elected Member, National Academy of Science
1982 Elected Fellow, National Academy of Arts and Sciences
CSO, Providence St. Joseph Health
President and Co-Founder of the Institute for Systems Biology in Seattle, WA
Chairman and Founder of the Department of Molecular Biotechnology at the UW
Caltech Faculty Member — Chair of Biology for 10 years
Senior Investigator, National Cancer Institute, National Institutes of Health
The Johns Hopkins School of Medicine