ISB News

Three Collaborative Projects Announced for ISB’s 2023 Innovator Award Program

ISB kicked off the seventh year of our successful Innovator Award Program by announcing three collaborative projects. This internal program is designed to support novel research ideas that cut across disciplines and research groups.

Dr. Leroy Hood, Popular Mechanics

Leroy Hood Wants To Show You How To Live for a Really, Really Long Time

Popular Mechanics interviewed ISB Co-founder and Professor Dr. Lee Hood for an article titled “Leroy Hood Wants To Show You How To Live for a Really, Really Long Time.” The story features Hood’s big-data approach and a focus on disease prevention – all in the quest to help us live longer.

Revolutionizing Healthcare: Exploring the Age of Scientific Wellness for Optimal Health and Disease Prevention

In their new book, “The Age of Scientific Wellness: Why the Future of Medicine is Personalized, Predictive, Data-Rich, and In Your Hands,” Drs. Lee Hood and Nathan Price introduce a new way of thinking about healthcare – a focus on preventing diseases and optimizing overall wellness.

LA Times Image

New Alzheimer’s drugs are costly and controversial. Are we going about this all wrong?

There is tremendous market and media frenzy around new Alzheimer’s disease drugs, but their efficacy is contested while the potential of prevention is untapped and underreported, Drs. Lee Hood and Nathan Price wrote in an opinion piece published by the Los Angeles Times.

“Armchair Expert with Dax Shepard” podcast welcomes Lee Hood and Nathan Price

Drs. Lee Hood and Nathan Price, authors of “The Age of Scientific Wellness,” were interviewed by actor and podcaster Dax Sheperd about their new book, and they discussed how AI is changing the medical industry, how infectious disease has impacted our world, the effectiveness of prescriptions, and much more.

Dr. Hadlock

Dr. Jennifer Hadlock Promoted to Associate Professor

Dr. Jennifer Hadlock – an expert in machine learning, immune-mediated inflammatory disease, and maternal/fetal health – has been promoted to associate professor. The Hadlock Lab is an interdisciplinary team that aims to accelerate translational research by integrating clinical data into systems biology at scale.

Beyond the Scale: How Multiomics and Biological BMI Can Help Achieve Optimal Health

ISB researchers have constructed a biological BMI that provides a more accurate representation of metabolic health and is more varied, informative and actionable than the long-used classical BMI. ISB Senior Research Scientist Dr. Noa Rappaport discussed biological BMI in a Research Roundtable presentation. 

The AI Will See You Now

This essay published by The Wall Street Journal is adapted from “The Age of Scientific Wellness,” the new book by Dr. Lee Hood, co-founder and professor of the Institute for Systems Biology, and Dr. Nathan Price, chief science officer of Thorne HealthTech.

Building a Better BMI

ISB researchers have constructed biological body mass index (BMI) measures that offer a more accurate representation of metabolic health and are more varied, informative and actionable than the traditional, long-used BMI equation. The work was published in the journal Nature Medicine. 

How Immune Cells ‘See’ and Respond to Mutations in Cancer Cells

In a just-published paper in the journal Nature, a collaborative team of researchers from ISB, UCLA, PACT Pharma, and beyond analyzed T-cell responses in melanoma patients who were treated with different immune checkpoint inhibitors, and how those responses evolved over time.

How Bacteria Build Communities That Can Impact Your Health

Bacteria are much more than single-celled organisms swimming around. Bacteria also form communities called biofilm, and work together to maintain the microbial community. Biofilm is just one research area of ISB’s Kuchina Lab. In this Research Roundtable presentation, ISB Assistant Professor Dr. Anna Kuchina details her work studying biofilms.

Ginny Ruffner and Dr. Jim Heath Explore the Intersection of Art and Science

Renowned artist Ginny Ruffner and ISB President Dr. Jim Heath delivered a lecture at Town Hall Seattle about the intersection of art and science. They spoke about how creation stories tie scientists and artists together, and how their approaches are both similar and different from that point on.

Daniel Chen Earns Prestigious Marshall Scholarship

As an undergraduate researcher in the Heath Lab, Chen has made major contributions to ISB’s research into COVID-19 and Long COVID. He will be pursuing a master’s degree in biological sciences and genomic medicine and conducting genomic medicine research at the Sanger Institute at the University of Cambridge in the United Kingdom.

ISB Associate Professor Dr. Sean Gibbons

Dr. Sean Gibbons Promoted to Associate Professor

Dr. Sean Gibbons – an expert in microbial ecology and evolution, computational systems biology, the human gut microbiome and its impacts on health, and head of ISB’s Gibbons Lab – has been promoted to Associate Professor. “Sean’s achievements since joining ISB in 2018 as a Washington Research Foundation Distinguished Investigator have been spectacular,” ISB President Dr. Jim Heath said. “With his focus on the microbiome, he brought a whole new…

AmeriCorps Member Sara Calder Joins ISB as Systems Health and STEM Coordinator

Sara Calder recently joined ISB as Systems Health and STEM Coordinator, and is our second-ever AmeriCorps member. In this Q&A, Calder shares her education journey, her future plans, and much more.

In First-of-Its-Kind Trial, Scientists Use CRISPR to Treat Cancer

Scientists for the first time have used CRISPR to substitute a gene to treat patients with cancer. The remarkable findings were published in the journal Nature and presented at the Society for Immunotherapy of Cancer (SITC) 2022.

The Gut Microbiome’s Supersized Role In Shaping Our Metabolome

ISB researchers have shown which blood metabolites are associated with the gut microbiome, genetics, or the interplay between both. Their findings, published in the journal Nature Metabolism, have promising implications for guiding targeted therapies designed to alter the composition of the blood metabolome to improve human health.

COCOA Trial Results Show Diet, Exercise Help Some with Dementia

The recently completed, ISB-led Coaching for Cognition in Alzheimer’s (COCOA) trial shows that diet and exercise can help people suffering from dementia. Senior Research Scientist Dr. Jared Roach discussed the findings in a Research Roundtable presentation.