Tissue-and serum-derived glycoproteins and methods of their use

Issue Date: 
May 3, 2007
Inventors: 

Hui Zhang, Rudolf H. Aebersold

Abstract: 

The present invention is directed generally to tissue-derived glycoproteins and glycosites detectable in plasma via mass spectrometric analysis of glycoproteins from both tissues and blood. The invention also provides methods for identifying tissue-derived glycoproteins and glycosites in plasma, panels of detection reagents for detecting same, as well methods for detecting disease using such panels. The invention further provides a database of tissue-derived glycoproteins and glycosites detectable in plasma.

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