SEATTLE, WA , March 11, 2010 – The Institute for Systems Biology (ISB) has analyzed the first whole genome sequences of a human family of four. The findings of a project funded through a partnership between ISB and the University of Luxembourg was published online today by Science on its Science Express website. It demonstrates the benefit of sequencing entire families, including lowering error rates, identifying rare genetic variants and identifying disease-linked genes.
SEATTLE, WA , March 8, 2010 – The Institute for Systems Biology, an independent, non-profit biomolecular research institute, has received a $6 million gift from a California venture capitalist and philanthropist to support strategic organizational objectives.
The donor, who wishes to remain anonymous, is designating his gift over a period of five years to:
SEATTLE, WA , January 6, 2010 – Institute for Systems Biology research papers have the highest scientific impact in the United States and the third highest in the world, according to a report evaluating research-centered organizations released in December by the SCImago Research Group, based in Spain.
SEATTLE, WA , December 17, 2009 – More than 70 leaders in peroxisome research from 14 nations around the globe gathered at the Institute for Systems Biology recently to share and discuss advances in the understanding of peroxisomes, which are cellular organelles responsible for the metabolism of fatty acids and ridding the cell of toxic materials. Required for life, malfunctioning peroxisomes cause devastating, and often fatal, neuronal and metabolic disorders in infants and children.
SEATTLE, WA , Nov 10, 2009 – The National Institutes of Health (NIH) has awarded the Institute for Systems Biology, a non-profit biomolecular research institute based in Seattle, WA, nearly $8 million to help identify new drug targets and therapies for many of the most lethal cancers, in one of the most significant endeavors since the Human Genome Project: The Cancer Genome Atlas (TCGA).
New York, – June 6, 2008 – Three of the United States' most prominent biomedical science leaders have been tapped by the government of Luxembourg for an unprecedented international collaboration to establish a bioscience center of excellence in the heart of the European Union.
SEATTLE, April 13, 2009 – Researchers at the Institute for Systems Biology (ISB) have demonstrated a new computational method for getting the most biological information out of huge and growing sets of genetic interaction data. A paper addressing the development has been published in the April edition of PLoS Computational Biology at http://www.ploscompbiol.org/doi/pcbi.1000347.
SEATTLE, March 24, 2009 – Researchers at the Institute for Systems Biology (ISB) in Seattle and the McLaughlin Research Institute in Great Falls, Montana, published today in Molecular Systems Biology a ground-breaking study which modeled the progression of degenerative brain diseases, one of which is "mad cow disease," that are caused by misfolded proteins called "prions". The paper can be accessed at http://www.nature.com/msb/index.html.
SEATTLE, February 18, 2009 – Researchers at the Institute for Systems Biology in Seattle and the University of British Columbia have develop a new fully automated microfluidic experiment platform for conducting live-cell experimentation that enables high throughput imaging and on-chip microenvironment manipulation.
A paper describing the platform was published recently in the Proceedings of the National Academy of Sciences.