News

First Whole Genome Sequencing of Family of Four Reveals New Genetic Power

March 11, 2010

SEATTLE, WA , March 11, 2010 – The Institute for Systems Biology (ISB) has analyzed the first whole genome sequences of a human family of four. The findings of a project funded through a partnership between ISB and the University of Luxembourg was published online today by Science on its Science Express website. It demonstrates the benefit of sequencing entire families, including lowering error rates, identifying rare genetic variants and identifying disease-linked genes.

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Institute for Systems Biology Receives $6 Million Gift from Anonymous California Donor

March 8, 2010

SEATTLE, WA , March 8, 2010 – The Institute for Systems Biology, an independent, non-profit biomolecular research institute, has received a $6 million gift from a California venture capitalist and philanthropist to support strategic organizational objectives.

The donor, who wishes to remain anonymous, is designating his gift over a period of five years to:

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Institute for Systems Biology Research Papers have Highest Scientific Impact in the United States according to International Report

January 6, 2010

SEATTLE, WA , January 6, 2010 – Institute for Systems Biology research papers have the highest scientific impact in the United States and the third highest in the world, according to a report evaluating research-centered organizations released in December by the SCImago Research Group, based in Spain.

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The Institute for Systems Biology Hosts International Peroxisome Research Meeting

December 17, 2009

SEATTLE, WA , December 17, 2009 – More than 70 leaders in peroxisome research from 14 nations around the globe gathered at the Institute for Systems Biology recently to share and discuss advances in the understanding of peroxisomes, which are cellular organelles responsible for the metabolism of fatty acids and ridding the cell of toxic materials. Required for life, malfunctioning peroxisomes cause devastating, and often fatal, neuronal and metabolic disorders in infants and children.

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ISB to Play Key Role in National Effort to Map Cancer Genome

November 10, 2009

SEATTLE, WA , Nov 10, 2009 – The National Institutes of Health (NIH) has awarded the Institute for Systems Biology, a non-profit biomolecular research institute based in Seattle, WA, nearly $8 million to help identify new drug targets and therapies for many of the most lethal cancers, in one of the most significant endeavors since the Human Genome Project: The Cancer Genome Atlas (TCGA).

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Leading U.S. Bioscience Pioneers Enter International Collaboration with Government of Luxembourg to Accelerate Biomedical Research

June 6, 2009

New York, – June 6, 2008 – Three of the United States' most prominent biomedical science leaders have been tapped by the government of Luxembourg for an unprecedented international collaboration to establish a bioscience center of excellence in the heart of the European Union.

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ISB Researchers Demonstrate Computational Method for the Maximizing Biological Information from Genetic Interaction Data

April 13, 2009

SEATTLE, April 13, 2009 – Researchers at the Institute for Systems Biology (ISB) have demonstrated a new computational method for getting the most biological information out of huge and growing sets of genetic interaction data. A paper addressing the development has been published in the April edition of PLoS Computational Biology at http://www.ploscompbiol.org/doi/pcbi.1000347.

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Systems Biology Provides First Global Analysis of Prion Disease in a Mouse Model

March 24, 2009

SEATTLE, March 24, 2009 – Researchers at the Institute for Systems Biology (ISB) in Seattle and the McLaughlin Research Institute in Great Falls, Montana, published today in Molecular Systems Biology a ground-breaking study which modeled the progression of degenerative brain diseases, one of which is "mad cow disease," that are caused by misfolded proteins called "prions". The paper can be accessed at http://www.nature.com/msb/index.html.

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