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Brady Bernard

Computational and theoretical modeling of biological systems to complement experimental investigation. Structure-guided prediction and design of biomolecular interactions with an emphasis in drug discovery. Structural bioinformatics and characterization of therapeutic targets. Atomic and molecular level investigation and inference of biological networks in health and disease.

Publications Outside of ISB

Movahedzadeh, F., Balasubramaniam, V., Bernard, B., Iyer, S., Samudrala, R., Franzblau, S., Balganesh, T. (2010) Anti-tuberculosis agents: A rational approach for discovery and development, in Genomic and computational tools for infectious diseases: A translational approach (Willy Valdivia-Granda, editor), Springer.

Bernard, B. and Samudrala, R. (2009) A generalized knowledge-based discriminatory function for biomolecular interactions. Proteins, 76(1):115-128. PMID 19127590, PMCID PMC2891153.

Merkley, E.D., Bernard, B., Daggett, V. (2008) Conformational changes below the Tm: molecular dynamics studies of the thermal pretransition of ribonuclease A. Biochemistry, 47(3):880-92. PMID 18161991, PMCID PMC2532537.

Armen, R.S., Bernard, B., Day, R., Alonso, D.O., Daggett, V. (2005) Characterization of a possible amyloidogenic precursor in glutamine-repeat neurodegenerative diseases. Proc Natl Acad Sci U S A, 102(38):13433-8. PMID 16157882, PMCID PMC1224618.