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David J. Reiss
Area of Expertise
Computational Biology
Statistical Modeling
Current Position
Senior Research Scientist
Degree
Ph.D., Astronomy, University of Washington, 1999
Research Interests
Dr. Reiss's research activities include statistical modeling of transcript and protein level data, detection and analysis of DNA and protein sequence motifs, and integration of disparate biological data types for the gathering of system-wide insights. He has integrated models of protein-protein interaction data with the detection of protein sequence motifs, microarray data and different types of interaction networks (protein-protein, protein-DNA, metabolic, etc.) with the detection of DNA sequence motifs, and protein- and mRNA expression levels. His studies currently focus on the systems biology of Halobacterium NRC-1, and is directed toward modeling its global gene regulatory network.
Selected Publications
Reiss DJ, Bonneau R, Baliga NS. Integrated biclustering of heterogeneous genome-wide datasets for the inference of global regulatory networks. BMC Bioinformatics, In press.
Bonneau R, Reiss DJ, Shannon P, Facciotti M, Hood L, Baliga NS, Thorsson, N. The Inferelator: an algorithm for learning parsimonious regulatory networks from systems-biology data-sets. 2006 Genome Biology, 7:R36.
Reiss DJ, Avila-Campillo I, Thorsson V, Schwikowski B, Galitski T. Tools enabling the elucidation of molecular pathways active in human disease: Application to Hepatitis C virus infection. 2005 BMC Bioinformatics 6:154
Reiss DJ, Schwikowski, B. Predicting protein-peptide interactions via a network-based motif sampler. 2004. Bioinformatics Vol. 20 Suppl. 1 i274-i282
Riess AG, Filippenko AV, Challis P, Clocchiattia A, Diercks A, Garnavich PM, Gilliland RL, Hogan CJ, Jha S, Kirshner RP, Leibundgut B, Phillips MM, Reiss D, Schmidt BP, Schommer RA, Smith RC, Spyromilio J, Stubbs C, Suntzeff NB, Tonry J. Observational Evidence from Supernovae for an Accelerating Universe and a Cosmological Constant. Astron. J. 116 (1998) 1009-1038
Relevant links
David's CV and public web site
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