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ISB Researchers Demonstrate Computational Method for the Maximizing Biological Information from Genetic Interaction Data

April 13, 2009

SEATTLE, April 13, 2009 – Researchers at the Institute for Systems Biology (ISB) have demonstrated a new computational method for getting the most biological information out of huge and growing sets of genetic interaction data. A paper addressing the development has been published in the April edition of PLoS Computational Biology at http://www.ploscompbiol.org/doi/pcbi.1000347.

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Systems Biology Provides First Global Analysis of Prion Disease in a Mouse Model

March 24, 2009

SEATTLE, March 24, 2009 – Researchers at the Institute for Systems Biology (ISB) in Seattle and the McLaughlin Research Institute in Great Falls, Montana, published today in Molecular Systems Biology a ground-breaking study which modeled the progression of degenerative brain diseases, one of which is "mad cow disease," that are caused by misfolded proteins called "prions". The paper can be accessed at http://www.nature.com/msb/index.html.

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ISB Researchers Develop Fully Automated, High Throughput Microfluidic Experiment Platform

February 18, 2009

SEATTLE, February 18, 2009 – Researchers at the Institute for Systems Biology in Seattle and the University of British Columbia have develop a new fully automated microfluidic experiment platform for conducting live-cell experimentation that enables high throughput imaging and on-chip microenvironment manipulation.

A paper describing the platform was published recently in the Proceedings of the National Academy of Sciences.

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